It’s 1978, and Ave Maria Mulligan is the thirty-five-year-old self-proclaimed spinster of Big Stone Gap, a sleepy hamlet in the Blue Ridge Mountains of Virginia. She’s also the local pharmacist, the co-captain of the Rescue Squad, and the director of The Trail of the Lonesome Pine, the town’s long-running Outdoor Drama. Ave Maria is content with her life—until, one fateful day, her past opens wide with the revelation of a long-buried secret that will alter the course of her life. Before she knows it, Ave Maria is fielding marriage proposals, trying to claim her rightful inheritance, and planning the trip of a lifetime to Italy—one that will change her view of the world and her own place in it forever.